Phytochemical, Antioxidant, And Antibacterial Analysis Of Ethanol Extract Of Garcinia Kola Seeds
Ibrahim Chukwudi Okonkwo
Department of Microbiology, Faculty of Science, University of Abuja, Abuja, FCT, Nigeria
Abstract
Garcinia kola is a medicinal plant that has been used for centuries in the treatment of ailment in subSaharan Africa, this is because all parts of this plant have been mentioned to be very important but the seed is the most used part. This study was conducted to test for the antimicrobial and antioxidant activity of ethanol extract of G. kola seed against some microorganisms such as Streptococcus pyogenes, Salmonella paratyphi, Staphylococcus aureus and Escherichia coli. Agar well diffusion method was used to determine the inhibitory effect of different concentration of the extract on the test organisms. The extract was found to inhibit the growth of these organisms as it gave wider zones of inhibition in Streptococcus pyogene s, 17 ± 1.0 mm, and Staphylococcus aureus, 8.0 ± 0.0 mm, and minimal inhibitory zones in Escherichia coli, 6.0 ± 0.0 mm, and Salmonella paratyphi, resistant. Garcinia kola seed showed a slightly lower percentage inhibition when compared to that of vitamin C in antioxidant screening as it gave percentage inhibition of 57.11 for 0.5 mg/ml, 57.32 at 0.25 mg/ml, 53.77 at 0.125 mg/ml, 41.53 at 0.0625 mg/ml and 53.77 at 0.03125 mg/ml. As a result G. kola exhibit antioxidant properties towards preventing free radi cal from causing damage to the cell thus, this provides justification for its medical use in the treatment of different diseases.